3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED

3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED - Names and Identifiers

Name	3-Aminomethyl-1-N-Cbz-piperidine
Synonyms	N-CBZ-3-AMINOMETHYLPIPERIDINE N-Cbz-3-aminomethylpiperidine 3-AMINOMETHYL-1-N-CBZ-PIPERIDINE 3-Aminomethyl-1-N-Cbz-piperidine 3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED BENZYL 3-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE benzyl 3-(aminomethyl)piperidine-1-carboxylate Benzyl 3-(Aminomethyl)piperidine-1-carboxylate 3-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 1-Piperidinecarboxylic acid, 3-(aminomethyl)-, phenylmethyl ester
CAS	315717-76-1
InChI	InChI=1/C14H20N2O2/c15-9-13-7-4-8-16(10-13)14(17)18-11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11,15H2

3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED - Physico-chemical Properties

Molecular Formula	C14H20N2O2
Molar Mass	248.32
Density	1.125±0.06 g/cm3(Predicted)
Boling Point	385.7±25.0 °C(Predicted)
Flash Point	187.1°C
Vapor Presure	3.73E-06mmHg at 25°C
pKa	10.12±0.29(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.55

3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED - Risk and Safety

Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

3-(AMINOMETHYL)PIPERIDINE, N1-CBZ PROTECTED - Introduction

It is an organic compound, also known as Cbz-PIP or AMC-piperidine. It has a chemical formula of cis-H-N-O, and its structure contains an amino group, a methyl group and a N-Cbz protecting group.

In terms of nature, it is a white solid with medium solubility. It is usually a crystal that is easily cleared and stable under dry conditions.

It has a wide range of uses in organic synthesis. It is often used as an intermediate in the synthesis of drugs and biologically active molecules. Because of its N-Cbz protecting group, it can be used as an amino protecting agent in organic synthesis, which can protect the amino group from the interference of other reactants. In addition, it can be used for the synthesis of polypeptides, carbohydrates and natural products.

on the preparation method, the synthesis of pyridine is generally achieved by the reaction of piperidine carbamate. The specific step is to first react piperidine with chloroformic acid to form piperidine chloroformate, and then form piperidine by amination reaction.

In terms of safety information, the toxicity is low, but it still needs to be handled properly. Avoid contact with skin and eyes, and avoid inhalation or ingestion during use or storage. When operating in the laboratory, wear appropriate personal protective equipment and follow relevant safe operating procedures and instructions for use.

Last Update：2024-04-10 22:30:50